In the early 1990s, my laboratory derived ES cells from an Old World monkey (the rhesus macaque) and a New World monkey (the common marmoset), work that led to the derivation of human ES cells. Much of the initial work in my laboratory after that derivation focused on establishing human ES cells as an accepted, practical model system. We are now focused on using these tools to understand the basic biology of pluripotency. For example, we use several conditions that induce uniform differentiation to specific lineages to study in detail how ES cells decide to exit the pluripotent state and become restricted in their potential, and we use a hematopoietic model system to study how that process of restriction can be reversed.
if nothing else, you have to respect the #Superbowl for its commitment to keeping Roman numerals relevant.
